Key Details:
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Strengths:
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Metformin: 500mg
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Sitagliptin: 50mg
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Class: Biguanide + DPP-4 Inhibitor
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Use: For adults with Type 2 diabetes, as an adjunct to diet and exercise
How It Works:
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Metformin: Lowers hepatic glucose output and improves peripheral insulin sensitivity
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Sitagliptin: Enhances the body’s natural incretin system, increasing insulin and lowering glucagon post-meal
Dosage:
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Typically taken twice daily with meals to reduce gastrointestinal side effects
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Dosage should be individualized and adjusted by a healthcare provider
Precautions:
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Not for use in patients with Type 1 diabetes or diabetic ketoacidosis
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Monitor kidney function regularly
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Use with caution in patients with renal impairment or risk of pancreatitis
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May need dose adjustments in elderly patients
Common Side Effects:
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Nausea or upset stomach
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Diarrhea
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Headache
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Upper respiratory tract infection
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Rare: Lactic acidosis (Metformin-related), pancreatitis (Sitagliptin-related)
Storage:
Store at room temperature, away from moisture and heat.
