This combination tablet contains Metformin 1000mg and Sitagliptin 50mg, used to manage Type 2 diabetes mellitus in adults. It helps improve blood sugar control by targeting multiple pathways: Metformin lowers glucose production in the liver and improves insulin sensitivity, while Sitagliptin (a DPP-4 inhibitor) increases insulin release and decreases glucagon levels in response to meals.
Key Details:
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Strengths:
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Metformin: 1000mg
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Sitagliptin: 50mg
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Class: Biguanide + DPP-4 Inhibitor
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Use: Adjunct to diet and exercise for adults with Type 2 diabetes
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Form: Oral tablet
How It Works:
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Metformin: Reduces hepatic glucose output and enhances insulin sensitivity
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Sitagliptin: Enhances incretin hormones to increase insulin secretion and reduce glucagon after meals
Dosage:
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Typically taken once or twice daily with meals, depending on individual treatment needs
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Dosage and timing should be determined by a healthcare provider
Precautions:
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Not for Type 1 diabetes or diabetic ketoacidosis
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Use cautiously in patients with kidney or liver impairment
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Monitor kidney function regularly
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May need to be temporarily discontinued before contrast imaging procedures
Common Side Effects:
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Nausea or upset stomach (Metformin-related)
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Diarrhea
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Headache
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Upper respiratory tract infections
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Rare: Lactic acidosis (Metformin), pancreatitis (Sitagliptin)
Storage:
Store at room temperature, in a dry place, away from heat and moisture.
